{"id":15669,"date":"2025-11-14T08:00:00","date_gmt":"2025-11-14T05:00:00","guid":{"rendered":"https:\/\/kindora.com\/?p=15669"},"modified":"2025-11-14T10:22:04","modified_gmt":"2025-11-14T07:22:04","slug":"melatonina-insuficienta-cardiaca-studiu","status":"publish","type":"post","link":"https:\/\/kindora.com\/ro\/melatonina-insuficienta-cardiaca-studiu\/","title":{"rendered":"Consumul de melatonin\u0103 pe termen lung, asociat cu insuficien\u021ba cardiac\u0103, potrivit unui studiu preliminar"},"content":{"rendered":"\n
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Utilizarea pe termen lung a suplimentelor cu melatonin\u0103 ar putea fi asociat\u0103 cu un risc mai mare de insuficien\u021b\u0103 cardiac\u0103, spitalizare \u0219i deces, potrivit unor noi cercet\u0103ri.<\/em><\/strong><\/p>\n\n\n\n

De\u0219i concluziile atrag aten\u021bia, exper\u021bii subliniaz\u0103 c\u0103 sunt preliminare \u0219i nu demonstreaz\u0103 c\u0103 melatonina cauzeaz\u0103 direct probleme cardiace.<\/em><\/strong><\/p>\n<\/div>\n\n\n\n

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\"persoana<\/figure>\n<\/div>\n<\/div>\n\n\n\n

Cercetarea de cinci ani a analizat 130.828 de adul\u021bi cu insomnie \u0219i a descoperit c\u0103 persoanele care au luat melatonin\u0103 prescris\u0103 timp de cel pu\u021bin un an au avut un risc cu 90% mai mare de insuficien\u021b\u0103 cardiac\u0103<\/strong>, comparativ cu participan\u021bii care aveau aceia\u0219i factori de s\u0103n\u0103tate, dar nu luau melatonin\u0103. Cei care utilizau melatonin\u0103 aveau, de asemenea, un risc de peste trei ori mai mare de a fi spitaliza\u021bi pentru insuficien\u021b\u0103 cardiac\u0103 \u0219i aproximativ de dou\u0103 ori mai multe \u0219anse de a muri din orice cauz\u0103. Studiul a fost prezentat la American Heart Association\u2019s Scientific Sessions 2025, \u00een noiembrie. <\/p>\n\n\n\n

Totu\u0219i, exper\u021bii sugereaz\u0103 s\u0103 nu consider\u0103m melatonina un pericol cert. Cercetarea are limit\u0103ri importante, nu a fost conceput\u0103 pentru a demonstra o rela\u021bie de tip cauz\u0103-efect \u0219i contrazice studii anterioare care indicau beneficii pentru s\u0103n\u0103tatea inimii.<\/p>\n\n\n\n

Melatonina \u0219i insuficien\u021ba cardiac\u0103 – ce presupune studiul <\/h2>\n\n\n\n

Participan\u021bii aveau \u00een medie 55 de ani, iar 61,4% erau femei. Cei care aveau specificat \u00een fi\u0219ele medicale un consum de melatonin\u0103 mai lung de un an au fost inclu\u0219i \u00een \u201egrupul melatonin\u0103\u201d, iar cei f\u0103r\u0103 astfel de \u00eenregistr\u0103ri au fost inclu\u0219i \u00een \u201egrupul f\u0103r\u0103 melatonin\u0103\u201d. Acest lucru introduce c\u00e2teva limit\u0103ri importante, semnalate de autori \u0219i de exper\u021bi independen\u021bi.<\/p>\n\n\n\n\t

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Baza de date include pacien\u021bi din \u021b\u0103ri \u00een care melatonina necesit\u0103 prescrip\u021bie medical\u0103 (precum Marea Britanie), dar \u0219i din \u021b\u0103ri unde se vinde f\u0103r\u0103 re\u021bet\u0103 (precum SUA).<\/p>\n\t\t<\/div>\n\t<\/div>\n\n\t\t<\/div>\n\n\n\n

Cercet\u0103torii nu au avut informa\u021bii despre severitatea insomniei participan\u021bilor sau despre existen\u021ba unor tulbur\u0103ri de s\u0103n\u0103tate mintal\u0103 – factori care pot influen\u021ba at\u00e2t consumul de melatonin\u0103, c\u00e2t \u0219i riscurile cardiovasculare, a declarat dr. Ekenedilichukwu Nnadi, autorul principal \u0219i medic rezident senior \u00een medicin\u0103 intern\u0103 la SUNY Downstate\/Kings County Primary Care din Brooklyn, \u00eentr-un comunicat de pres\u0103<\/a>.<\/p>\n\n\n\n

Mai mult de at\u00e2t, insomnia este asociat\u0103 cu risc crescut de infarct sau AVC. Dereglarea ritmului circadian – \u00een care melatonina joac\u0103 un rol important – \u0219i somnul insuficient sunt, de asemenea, corelate cu un risc mai mare de insuficien\u021b\u0103 cardiac\u0103.<\/p>\n\n\n\n

Fiind un studiu observa\u021bional, acesta nu poate demonstra c\u0103 melatonina a cauzat direct insuficien\u021ba cardiac\u0103. Sunt necesare studii suplimentare, inclusiv studii clinice randomizate, pentru a valida aceste rezultate.<\/p>\n\n\n\n

De asemenea, noile descoperiri nu explic\u0103 de ce melatonina ar putea afecta inima. Persoanele care iau melatonin\u0103 pe termen lung ar putea avea probleme subiacente, precum stresul sau tulbur\u0103rile de somn – factori care, de fapt, pot duce la insuficien\u021b\u0103 cardiac\u0103.<\/p>\n\n\n\n

Ce este insomnia<\/h2>\n\n\n\n
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Insomnia cronic\u0103, care afecteaz\u0103 aproximativ 10% din popula\u021bia global\u0103, este definit\u0103 prin dificultatea de a adormi sau readormi mai mult de 30 de minute, de p\u00e2n\u0103 la trei ori pe s\u0103pt\u0103m\u00e2n\u0103, pe o durat\u0103 mai mare de trei luni. Poate duce la probleme de memorie, energie diurn\u0103 sc\u0103zut\u0103, iritabilitate, afectarea func\u021biilor cognitive, performan\u021b\u0103 sc\u0103zut\u0103 la serviciu sau \u0219coal\u0103 \u0219i dificult\u0103\u021bi \u00een via\u021ba social\u0103.<\/p>\n\n\n\n

Un medic poate ajuta la determinarea cauzei – dac\u0103 insomnia apare ca problem\u0103 independent\u0103 sau ca rezultat al unei condi\u021bii medicale sau al stresului – \u0219i poate recomanda tratamentul potrivit: ajustarea rutinei de somn, terapie psihologic\u0103, terapie cognitiv-comportamental\u0103 pentru insomnie, medica\u021bie sau tratarea unei afec\u021biuni asociate.<\/p>\n<\/div>\n\n\n\n

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\"femeie<\/figure>\n<\/div>\n<\/div>\n\n\n\n

De ce nu este recomandat\u0103 utilizarea pe termen lung a melatoninei<\/h2>\n\n\n\n

Estim\u0103rile sugereaz\u0103 c\u0103 5 milioane de adul\u021bi americani \u0219i 4 milioane de copii iau melatonin\u0103 \u00een fiecare lun\u0103 – unul dintre cele mai utilizate suplimente pentru somn. Siguran\u021ba perceput\u0103 \u0219i accesibilitatea au alimentat aceast\u0103 cre\u0219tere \u00een ultimii ani. Aceste noi concluzii subliniaz\u0103 importan\u021ba consult\u0103rii unui specialist \u00eenainte de a lua melatonin\u0103 timp \u00eendelungat.<\/p>\n\n\n\n

Utilizarea pe termen scurt a melatoninei poate ajuta \u00een anumite tulbur\u0103ri de somn \u0219i poate chiar oferi unele beneficii cardiovasculare. Studii pe oameni \u0219i animale au sugerat c\u0103 melatonina poate reduce stresul oxidativ \u0219i poate \u00eembun\u0103t\u0103\u021bi func\u021bia ventriculului st\u00e2ng \u00een insuficien\u021ba cardiac\u0103. Acest fapt sugereaz\u0103 c\u0103 luarea suplimentelor cu melatonin\u0103 pe o perioad\u0103 scurt\u0103 nu are avea efecte nedorite. <\/p>\n\n\n\n

Alternative la melatonin\u0103<\/h2>\n\n\n\n

Administrarea pe termen scurt este considerat\u0103 \u00een general sigur\u0103, dar melatonina poate interac\u021biona cu unele medicamente sau poate provoca somnolen\u021b\u0103 diurn\u0103, grea\u021b\u0103, ame\u021beli sau dureri de cap \u00een anumite cazuri. (Descoper\u0103 totul despre alimente bune pentru somn<\/a>)<\/p>\n\n\n\n

\u201eImplica\u021biile utiliz\u0103rii pe termen lung nu sunt clare \u0219i sunt necesare mai multe studii. \u00cen acest moment, a\u0219 recomanda utilizarea celei mai mici doze posibile \u0219i pentru cea mai scurt\u0103 perioad\u0103 necesar\u0103\u201d, a declarat Jamie Alan, profesor asociat de farmacologie \u0219i toxicologie la Michigan State University, potrivit Verywell<\/a>.<\/p>\n\n\n\n

\"mana<\/figure>\n\n\n\n

Iat\u0103 c\u00e2teva alternative naturale la melatonin\u0103 care \u00ee\u021bi pot \u00eembun\u0103t\u0103\u021bi somnul:<\/p>\n\n\n\n

Magneziu<\/a> – Mul\u021bi speciali\u0219ti v\u0103d magneziul ca pe o alternativ\u0103 mai bl\u00e2nd\u0103 la melatonin\u0103, mai ales atunci c\u00e2nd somnul lipse\u0219te din cauza tensiunii \u0219i a stresului. Forme precum magneziul glicinat pot relaxa musculatura \u0219i pot lini\u0219ti sistemul nervos, ajut\u00e2nd corpul s\u0103 intre mai u\u0219or \u00eentr-o stare de calm \u00eenainte de culcare.<\/p>\n\n\n\n

L-teanina<\/strong> – Este un aminoacid care induce o stare de lini\u0219te f\u0103r\u0103 s\u0103 te fac\u0103 somnolent. Sprijin\u0103 neurotransmi\u021b\u0103tori precum GABA \u0219i serotonina, ceea ce ajut\u0103 mintea s\u0103 se \u201ea\u0219eze\u201d dup\u0103 o zi \u00eenc\u0103rcat\u0103. E o variant\u0103 excelent\u0103 dac\u0103 somnul \u00ee\u021bi este perturbat de stres sau g\u00e2nduri care nu se mai opresc.<\/p>\n\n\n\n

Valeriana<\/strong> – Este poate cel mai cunoscut remediu vegetal pentru somn. Nu func\u021bioneaz\u0103 identic la toat\u0103 lumea, dar multe persoane observ\u0103 c\u0103 adorm mai repede \u0219i dorm mai ad\u00e2nc. Un avantaj important: nu creeaz\u0103 dependen\u021b\u0103 \u0219i nici toleran\u021b\u0103 \u00een timp.<\/p>\n\n\n\n

GABA –<\/strong> Este un neurotransmi\u021b\u0103tor cu rol inhibitor, care \u201edomole\u0219te\u201d excitabilitatea nervoas\u0103. Suplimentele cu GABA pot ajuta atunci c\u00e2nd mintea r\u0103m\u00e2ne hiperactiv\u0103 seara, mai ales \u00een context de anxietate u\u0219oar\u0103 sau stres persistent.<\/p>\n\n\n\n

Terapia cognitiv-comportamental\u0103 pentru insomnie<\/strong> – este considerat\u0103 cea mai eficient\u0103 abordare pe termen lung. Lucreaz\u0103 at\u00e2t cu g\u00e2ndurile care \u00eentre\u021bin insomnia, c\u00e2t \u0219i cu obiceiurile de somn. Este o solu\u021bie profund\u0103, nu un \u201eplasture\u201d, \u0219i are rezultate mai bune dec\u00e2t medicamentele, \u00een timp.<\/p>\n\n\n\n

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\n\t\tPlante cu efect bl\u00e2nd pentru somn – Mu\u0219e\u021belul, passiflora \u0219i hameiul pot sus\u021bine relaxarea \u00eenainte de culcare. Mu\u0219e\u021belul calmeaz\u0103, passiflora poate ajuta \u00een fazele ini\u021biale ale somnului, iar hameiul este folosit tradi\u021bional pentru reducerea tensiunii mentale. Sunt op\u021biuni delicate pentru persoanele care nu tolereaz\u0103 bine suplimentele puternic sedative.\t<\/h4>\n<\/div>\n <\/div>\n\n\n\n

Un alt aspect important pentru un somn bun este s\u0103 ai grij\u0103 la mediul din camera \u00een care dormi<\/strong>. O camer\u0103 mai rece, cu \u00eentuneric, lini\u0219te \u0219i evitarea luminii albastre cu dou\u0103 ore \u00eenainte de culcare pot regla \u00een mod natural melatonina produs\u0103 de corp. Adesea, aceste ajust\u0103ri simple readuc somnul la normal f\u0103r\u0103 suplimente.<\/p>\n","protected":false},"excerpt":{"rendered":"

Utilizarea pe termen lung a suplimentelor cu melatonin\u0103 ar putea fi asociat\u0103 cu un risc mai mare de insuficien\u021b\u0103 cardiac\u0103, spitalizare \u0219i deces, potrivit unor noi cercet\u0103ri. De\u0219i concluziile atrag aten\u021bia, exper\u021bii subliniaz\u0103 c\u0103 sunt preliminare \u0219i nu demonstreaz\u0103 c\u0103 melatonina cauzeaz\u0103 direct probleme cardiace. Cercetarea de cinci ani a analizat 130.828 de adul\u021bi cu […]<\/p>\n","protected":false},"author":318,"featured_media":15677,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_glsr_average":0,"_glsr_ranking":0,"_glsr_reviews":0,"footnotes":""},"categories":[68,66],"tags":[],"class_list":["post-15669","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noutati","category-sanatate"],"acf":[],"yoast_head":"\nConsumul de melatonin\u0103, asociat cu risc de insuficien\u021b\u0103 cardiac\u0103<\/title>\n<meta name=\"description\" content=\"Utilizarea pe termen lung a suplimentelor cu melatonin\u0103 ar putea fi asociat\u0103 cu un risc mai mare de insuficien\u021b\u0103 cardiac\u0103.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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